Into Unscientific Chapter 354

  Chapter 354 Donkey Brother: Co-author I am the number one driving force for technological development?

  University of Science and Technology of China.

  Life Medicine Building.

  Four floors of medicinal chemistry laboratory.

   click—

  Following the sound of the door opening, Xu Yun hurried in from outside the house in a lab coat:

   "Old Qiu, what's the matter?"

   As a result, before he finished speaking, he noticed the figure of another person in the room:

   "Huh? Academician Zhao?"

   Exactly.

  At this time, besides the tool man Qiu Sheng, another old acquaintance of Xu Yun was sitting in the laboratory:

   Academician Zhao Zhengguo!

   is now the director of the Experimental Physics Center of the Institute of High Energy Physics, Chinese Academy of Sciences, and the person in charge who led the experiment on the Λ hyperon.

  He and Pan Shuai captured a brand new Λ hyperon by relying on the particle orbit calculated by Xu Yun.

   "Well, Xiao Xu, good afternoon."

  Zhao Zhengguo greeted Xu Yun, pointed at Qiu Sheng with a smile, and explained:

   "I want to talk to you about something today. When I first came to see you, Xiao Qiu said that you will be here soon, so I will stay here first."

   "But I'm not in a hurry, you two can deal with your affairs first, and you don't mind if I stay here and listen?"

  Xu Yun admired Zhao Zhengguo's character very much, so he quickly waved his hands:

   "I don't mind, of course I don't mind—and besides, how many people in China dare to kick you out?"

   After praising Zhao Zhengguo a little, Xu Yun turned his attention to Qiu Sheng:

   "Old Qiu, what's your situation?"

   Qiu Sheng glanced at Zhao Zhengguo who was sitting quietly listening, and waved to Xu Yun:

   "Come and see."

  Xu Yun hummed and walked over quickly.

  At this time, there was a stack of thick paper reports on the table in front of Qiu Sheng. After Xu Yun approached, Qiu Sheng handed him some pages:

   "Here, this."

  Xu Yun took the opportunity and looked it up on the spot:

   "The rotting rate of the Yian bacteria strain and the CCK-8 test report?"

   Students who were bacteria in their previous life should know it.

   There are many methods for laboratory bacterial activity detection, but generally only a few are commonly used.

  For example, chemiluminescence, that is, ATP luminescence.

  Adenosine triphosphate is composed of adenine, ribose and 3 phosphate groups. It releases more energy when hydrolyzed, and is the most direct energy source in the body.

  Exogenous firefly luciferin or luciferase will oxidize with ATP in the cell to generate photons.

  So the ATP content can be detected by monitoring the photometry, so as to analyze the cell activity and proliferation.

   In addition to the ATP luminescence method.

  CCK-8 is also a common and efficient detection method.

Its main component is water-soluble tetrazolium salt SST-8 (2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfobenzene )-2H-tetrazole monosodium salt), is a compound similar to MTT.

   In the presence of electron coupling reagents.

   It can be reduced by some dehydrogenases in mitochondria to produce orange-yellow water-soluble formazan.

  The formazan produced after SST-8 is bioreduced by intracellular dehydrogenase can be directly dissolved in the medium, and the more the cells proliferate, the faster the color will be.

   "Phosphatidylserine is mainly distributed in the inner layer of the plasma membrane, without asymmetrical changes."

   "Reduction potential value shifted by +228mV"

   "Spectrophotometer readings are 0.434, 0.437, 0.432"

  Xu Yun read line by line, and the numbers made him a little happy.

  When he discovered Yi'an Bacteria, Tian Liangwei generously sent Xu Yun a Micro-Matrix and a 350RPM orbital shaker.

  Although Tian Liangwei's goal is not "very pure", part of the reason is to let Xu Yun and others be a guinea pig for microfluidic interface nanoliter injection technology and high polymer feeding method.

  However, the accuracy improvement brought by these two devices to the laboratory is also visible to the naked eye.

After a few minutes.

  Xu Yun raised his head slowly, rubbed the report paper with his thumb, and asked Qiu Sheng:

   "Old Qiu, according to the test results, the activity of Yi'an bacteria is much higher than other strains of Arthrobush?"

  Qiu Sheng nodded heavily, picked up a can of yogurt from the table and took a sip:

   "That's right, according to experiments, the reproduction efficiency of Yi'an Bacteria is extremely high."

   "Under a certain density, the only thing that restricts their reproduction is the breeding environment of the product of the pentose phosphate pathway, or in a sense, the number of native donkey hairs."

"in addition."

   "Old Xu, the activity of Yi'an Bacteria is not simply higher than that of other Arthrobush species."

  Xu Yun frowned and glanced at him, then curled up the experiment report and hit Qiu Sheng on the head:

   "This is not the end of the chapter. Why are you pretending to be a riddle? Talk to people!"

   "I'm learning from you. Hey, don't hit me!"

  Qiu Sheng rubbed the back of his head, and pointed his chin toward the report in Xu Yun's hand:

   "Old Xu, do you still remember the way Yi'an bacteria kills Neisseria and anaerobic streptococcus?"

  Xu Yun nodded, and answered very simply:

   "Of course I remember, the bald head attacks."

  Neisseria and anaerobic streptococcus are bacteria that are abundant in human saliva, and they are also two of the important 'members' that cause bad breath.

  Yian Bacteria has an extremely efficient killing ability against these two types of bacteria, and its main method is to split the mycelium, and the mycelium will 'bind' the target bacteria.

  This attack method is like a person constantly taking off his hair to kill the enemy, so it is also called a hair loss attack by Xu Yun and Qiu Sheng.

  In the laboratory.

   Seeing that Xu Yun still didn't understand what he meant, Xu Yun had no choice but to mention it again:

   "Old Xu, haven't you thought of it yet?"

   "The moment Yi'an Bacteria emits mycelium, it is a kind of energy transformation, that is to say, it will emit"

   "Electrons! And a lot of them!"

   Electronics.

  These two light words suddenly turned into a thunderbolt when they were introduced into Xu Yun's mind from Qiu Sheng's mouth!

  In an instant.

  A tingling sensation suddenly rose from Xu Yun's tailbone and went straight into his mind!

   More than ten seconds passed.

  Xu Yuncai slowly came back to his senses, looked at Qiu Sheng blankly, and asked:

   "You mean"

   "Easy Bacteria, can it be used as a power-generating strain for microbial batteries?!"

  Qiu Sheng smiled, obviously very satisfied with Xu Yun's astonishment, and did not remember that when he saw the experimental results, his heart was even more shocked than Xu Yun at this time:

   "Congratulations, the answer is correct, Azkabanga ten points!"

  Xu Yun directly ignored the work of the tool man, and at this moment, his mind was completely on Yi Anjun.

   There is an old saying in China, which is called awakening the dreamer with one word.

  Now Xu Yun was completely shocked by Qiu Sheng's words, quickly connected the cause and effect together, and formed a general context of the incident in his heart:

   A month ago.

   After returning to reality.

  Xu Yun once organized a brainstorming session, and mentioned microbial batteries and hemostatic gelatin with Qiu Sheng and Zhou Shan.

  Especially microbial batteries, this project was directly established by Xu Yun as the goal of the next stage.

   After all, this is the technology with the thinnest barriers among all rewards. It is so thin that if you directly propose an idea, it will not surprise others at all.

  Because the concept of microbial batteries has been around for many years, the whole technology is actually very clear at the theoretical level, and there are only two barriers that are the most difficult:

  Power supply bacteria and current collection method.

   And right now, according to what Qiu Sheng said.

  Easy Bacteria seems to be a perfect fit for this requirement?

think carefully

   Seems quite reasonable?

  The area where Yi'an Bacteria was discovered was the sewer with the largest flow in the University of Science and Technology, surrounded by Nanako's lair, with millions of cockroaches.

  Easy Bacteria can clean a piece of pure land in that area, which means that its biological attributes must have two characteristics:

First.

   Can survive in harsh environments.

  This severe condition can be a sewer, but it can also be

   Storage tank for microbial batteries.

second.

  It must be very efficient at cleaning.

   Otherwise, the next round of sewage will come again before the first round is cleaned up, and it is impossible to form the "pure land" that Xu Yun saw at the beginning.

to some extent.

   This is also a kind of life evolution by natural selection.

   On this basis.

  When Yi'an Bacteria starts to engulf other bacteria, the whole process needs to consume, or convert a lot of energy.

  The phagocytosis of the hair structure will generate an action potential.

   According to Qiu Sheng's test results.

  The electrical activity of Yian bacteria is very powerful and efficient, even far exceeding the current mainstream strain of Shewanella in microbial battery experiments.

Of course.

  Easy bacteria suitability does not mean that the microbial battery of Yian bacteria can be produced immediately.

   There are still many links in front of Xu Yun that need to be considered or breakthroughs.

   For example, how to provide energy for Yian Bacteria?

   Can't let the user spit directly into the storage slot?

   Not to mention how much electricity can be generated by a mouthful of saliva, this behavior alone is quite disgusting

  Perhaps some outdoor enthusiasts can accept this, but it is obviously impossible for Xu Yun to only take care of this group - if small microbial batteries can be released, the audience of business travelers and students is much larger than the circle of outdoor enthusiasts.

   In addition, how to collect electrons is also a technical barrier. It can only be said that it is easier than the most difficult bacteria selection.

   Just like this.

  The collection of donkey hair will increase again.

   Then Xu Yun put away the report and asked Qiu Sheng again:

   "I see, Lao Qiu, is there anything else?"

  Xu Yun's words were just a casual question, but Qiu Sheng actually nodded his head unexpectedly:

   "Well, there is one more thing, which is also related to the biotechnology you mentioned earlier-do you remember the hemostatic gelatin you mentioned?"

  Xu Yun was slightly taken aback:

   "Of course I remember, why, you have also made progress in the hemostatic gelatin?"

   "Strictly speaking, progress is not considered."

  Qiu Sheng shook his head and explained:

   “It was just in the course of my research that I found a material direction that seemed to work.”

  Xu Yun frowned even more upon hearing this:

   "The research process? I remember that we haven't established a project for coagulation gelatin, have we?"

  Xu Yun's remarks are naturally not questioning Qiu Sheng's petty tricks in private. The relationship between him and Qiu Sheng in two lifetimes has given him an extraordinary degree of trust in Qiu Sheng.

   So what he said was literally:

  Hemostatic gelatin was just an idea casually mentioned by Xu Yun during the brainstorming period. He didn't even do the preliminary demonstration, let alone start the research project.

  Therefore, there must be no relevant equipment and materials in the laboratory at present. How can Qiu Sheng produce results out of thin air?

  Seeing Xu Yun's bewildered expression, Qiu Sheng opened the drawer and took out a test tube.

  I saw in the test tube, impressively placed

  Another tuft of donkey hair.

   Then Qiu Sheng shook the test tube a few times and explained:

   "Old Xu, haven't I been doing the amplification of Yi'an Bacteria all this time? I used a lot of donkey hair as the culture medium."

   "Since we want to screen the most suitable culture medium, it is natural to add some other substances as a control group to optimize the most suitable amplification environment, right?"

  Xu Yun nodded, and Qiu Sheng's words are not difficult to understand:

   "Exactly.

   Then Qiu Sheng continued:

   "As a result, when I was doing quantification, I suddenly found that a tuft of donkey hair was stained with some mucus. After standing with benzoquinoline for a period of time, this mucus will form a very high-viscosity colloidal object."

   "So I thought of the coagulated gelatin you mentioned, and tried a rheometer to measure the longitudinal adhesion of that substance, and the result."

   "Its viscosity curve exceeds 860! It is more than six times that of 502 glue!"

Note:

  Out of the ICU, I finally breathed a sigh of relief. Last night outside the ICU, I actually had a time code, but I really didn't have any mood or status. I could only code in the morning and slipped to sleep.

  (end of this chapter)

Chapter end