Into Unscientific Chapter 185

  Chapter 185 Tone nemesis and the fetters of thousands of years? (6.6K)

   Qiu Sheng.

  Height 186, weight 70 kg, thick hair, handsome.

  HKUST Ph.D. in Biology, a school scholarship winner, is the ultimate template that almost every boy dreams of.

  But such a seemingly perfect person has an unspeakable hidden secret:

  He has breath.

  According to Uptodate statistics.

  The incidence rate of local bad breath is about 30%, that is, almost 1 out of every 3 people suffers from bad breath.

  It's just that in most cases, we have smelled the bad breath for a long time, and we have adapted to the bad breath, so we don't feel much.

  The cause of bad breath is actually very simple. To put it bluntly, there are two common causes:

    20% due to Helicobacter pylori, 80% due to microbial metabolism in the oral cavity.

  The latter contains a large number of previously mentioned bacteria such as Neisseria and anaerobic streptococci.

   Actually.

  There are many types of bacteria in the human mouth, and there are about 5,600 common species.

   There are pathogenic bacteria, non-pathogenic bacteria, conditional pathogenic bacteria and so on.

  Generally.

   In every gram of tartar in a normal healthy person, 10 billion bacteria can be found.

  With the secretion of saliva, these bacteria will decompose the food residue remaining in the teeth gap into organic amines, ammonia, sulfide and so on.

  It smells like that after long-term accumulation

Of course.

   There is also a relatively rare situation:

  It is a problem with a person's rectum, causing the smell of some excrement to flow directly into the mouth.

   This kind of situation does exist, but it has to be attributed to the complications of intestinal diseases, and it does not belong to the concept of bad breath that is usually mentioned.

   "Old Xu, the incidence rate of bad breath is 30%!"

  Inside the laboratory.

  Qiu Sheng propped his hands in front of the stage, leaned forward, and even showed a little ferocity in his agitated expression:

   "Think about the whole country, how many people are there in the world? If you can apply this new type of microorganism to clinical practice, your company will be able to walk on two feet!"

  As a breath patient, Qiu Sheng has tried almost all kinds of treatment methods on the market.

  But whether it is toothwash, mouthwash, or toothpaste that costs tens or even hundreds of dollars, the effect is not ideal.

   It's not that all of these are useless, the key is that their duration is too short.

  Take Listerine's mouthwash as an example.

   This should be a relatively representative brand in oral disinfection at present. Objectively speaking, the feeling after rinsing is really okay.

   But after a long time, the taste will reappear in the mouth.

  So the moment he read the experiment report, Qiu Sheng realized the value of this strain:

  Like imidacloprid, the discovery of this strain may not win a high-level award.

  But it has unimaginable commercial value!

  Compared to Qiu Sheng's agitation, Xu Yun's mood is much calmer, after all, the experience of the previous life is here:

   "Calm down first, Lao Qiu, the horoscope has not been written yet."

   "You are also engaged in scientific research, you should know how difficult it is to go from a laboratory to a popular product."

   "Aside from other things, the cultivation of plants is a big problem. The other is the direction of the finished product. Is it toothpaste, medicine or potion?"

   "The direction is different, the positioning is also different, and the difficulty also changes accordingly."

   "So in the final analysis, we still have to think about it in the long run. As the saying goes, you can't eat your ears in one breath."

  After hearing what Xu Yun said, Qiu Sheng gradually calmed down.

   Actually.

  He is not usually irritable and irritable. After all, he is quite stable in scientific research.

  However, he is an audience of a new species of microorganisms, and he has been troubled by bad breath for too long, so he lost his composure for a while.

   Then he was silent for a moment, and asked Xu Yun:

   "Old Xu, what are you going to do?"

  Xu Yun raised his eyelids and glanced at him, took a picture of his own card on the table, pointed to the USTC above and said:

   "Of course it's shaking people!"

   Half an hour later.

  Life Science Building.

director's office.

   "What? A new type of microbe?"

  Looking at Xu Yun and Qiu Sheng who looked serious, Tian Liangwei adjusted his black glasses in doubt:

   "New eukaryotic species, you can just vote in "FungalDiversity" directly, why did you come to me?"

   Friends who were microbes in the previous life should know it.

  In the field of biology, there are actually certain norms for the submission of papers on new species of microorganisms.

   For example, bacteria should be submitted to "IJSEM", the full name is "International Journal of Systematic and Evolutionary Microbiology", and other journals cannot be submitted.

  The new eukaryotic species is "Fungal Diversity", which is an international journal sponsored by the Kunzhi Institute of the Chinese Academy of Sciences.

   Ranks second among global journals in the field of mycology, and ranks third among all 188 SCI journals sponsored by relevant local academic institutions.

Of course.

  If you encounter a very valuable new type of microorganism, you may also make an exception and appear on "pnas", but basically it is rare for several years.

  University of Science and Technology and Kunzhi Institute are both affiliated units of the Chinese Academy of Sciences, so Xu Yun wants to deliver the relevant results, just contact the other party directly.

  At least in terms of situation, there is no need to go to the dean's office to notify Tian Liangwei with such a big fanfare.

  Looking at Tian Liangwei with a puzzled look on his face, Xu Yun couldn't help but turned his head and looked at Qiu Sheng.

   Then he took out a report from his body and handed it to Tian Liangwei:

   "Teacher, please take a look at this first."

  Tian Liangwei didn't speak, but took the report and read it:

   "A new species of Arthroplexia. Oval shape with a width of 1.5 μm."

  The content in front of the report is mainly the graphic data of the new species, which seems to be purely a new type of fungus.

   But as the line of sight moves down.

  His gaze sharpened suddenly.

After a few minutes.

  Tian Liangwei raised his head solemnly, and said to Xu Yun:

   "Xiao Xu, is this data accurate?"

  Xu Yun nodded heavily, affirming:

   "It's accurate. Before coming here, we collected multiple saliva samples and conducted multiple control experiments."

   "Finally, it was found that the disinfecting effect of the new species of microorganisms is extremely amazing and stable, especially in the saliva sample of a friend of mine, the efficiency is even faster than other ordinary samples."

   Qiu Sheng:

  Tian Liangwei looked at the report again, was silent for a moment, and said:

   "If the new species is really as the report says, then its commercial value will be astonishingly high. Xiao Xu, do you have any ideas?"

  Xu Yun picked up the teacup and moistened his throat, then pointed to Qiu Sheng:

   "Old Qiu and I had a brief discussion on the way here, and finally we discussed a direction."

  Tian Liangwei straightened his body and became interested:

   "Oh? Which way? Mouthwash or spray?"

   "No, it's toothpaste."

"toothpaste?"

  Tian Liangwei was taken aback when he heard the words, but quickly realized:

   "A product similar to lysozyme toothpaste?"

  Xu Yun nodded and said:

   "That's right, it's somewhat similar to lysozyme toothpaste, but it's just an idea at the moment, and further experiments are needed on how to operate it."

toothpaste.

   This is the prototype of a product discussed by Xu Yun and Qiu Sheng.

  The concept of biological toothpaste can be traced back to 20 years ago, but the current development of this field is not fast.

  By 2022, there will be only one type of biological toothpaste on the market:

  Plant lysozyme toothpaste.

  Plant lysozyme can hydrolyze bacterial cell walls and dissolve a variety of oral bacteria. The plant lysozyme currently on the market is mainly extracted from figs.

   But it is the same as the mouthwash mentioned above.

  Although lysozyme toothpaste has a good disinfecting effect in the laboratory, the duration of the practice session is also limited.

  If I have to say it, it can only be said to be a little better than the IQ tax of enzyme toothpaste, but I am also sorry for its price.

   So it can be said.

  In the field of toothpaste, there is not yet a truly effective biological toothpaste.

   This is a huge and blank market.

  At the same time, compared with the previous imidacloprid, there is only one barrier in the preparation process of biological toothpaste:

   Inactivation.

  The so-called inactivation refers to a kind of beneficial bacteria that retains the original structure and characteristics of beneficial bacteria through special inactivation technology, but no longer has the ability to grow and reproduce.

  For example, in all the probiotic yogurts that everyone drinks, the technology of inactivating bacteria is used.

  You can imagine:

If there is a toothpaste that can be used for three months on the market, it can still implant beneficial flora in the oral cavity while cleaning the mouth. This beneficial flora will not only disinfect various pathogenic bacteria, but also decompose the bacteria in the teeth food scraps, producing calorie-free metabolites,

   Moreover, the taste of this metabolite is particularly pleasant. You can choose mint flavor, lemon flavor, etc. according to your preferences.

   In this way, the prospect of this product can be described in three words:

Who else?

Of course.

  This is only a vision of the future.

  Want to make new species into finished products, in addition to the barriers in the preparation of finished products, there are also many technical difficulties:

   Such as the unit density mentioned before.

  Not to mention a million doses of penicillin, at least 500,000 units.

   At the same time, how to ensure the timeliness of the flora is also a topic that requires careful research:

  It's definitely okay if you ask someone with bad breath to brush their teeth twice a day, and they can barely stick to it three times.

   But if you want to swipe five or six times, seven or eight times or even more?

  Then this kind of toothpaste will lose its actual value.

  Think here.

  Tian Liangwei couldn't help looking at Xu Yun, and asked:

   "Tell me, Xiao Xu, how can the courtyard or the college cooperate with you?"

  Xu Yun slightly shook the palm under the table, but he was still calm on the surface:

   "The first is the collection of samples. We found that this microorganism will excite green fluorescence when exposed to a wavelength of 365nm, so we hope to collect all-round strains of the underground pipelines in the school."

  Tian Liangwei nodded when he heard the words:

   "This is no problem. I can directly apply to the school board. The level is just to add a laser inspection during the hardware inspection process. It is not difficult."

   Actually.

  From the rewards given by the halo, it is not difficult to see that this type of new species only exists in the sewer pipe under the basketball court with a high probability.

  But Tian Liangwei and the others didn't know the news. From the perspective of an outsider, it is normal to start a blanket search.

  That's why Xu Yun came up with this idea, trying to make his discovery seem more accidental.

   Then Tian Liangwei paused, and continued:

   "Aside from all-round detection, what else?"

   "There is also equipment and financial support."

  Xu Yun leaned forward slightly, and naturally asked for a ticket:

   "Theoretically, the new species of microorganisms have high commercial value, which is just in line with the business scope of our Huadun Biological Sciences, so should the school?"

  Tian Liangwei glanced at Xu Yun and said:

   "No, isn't there still a lot of money in the company account?"

  In the previous financing process, the University of Science and Technology Innovation Fund, as the leader, invested a total of 8 million Huaxia coins in cash flow.

  The School of Physics of HKUST and the School of Life Sciences of HKUST each invested 2 million yuan, totaling 4 million yuan.

  Xu Yun injected 100 cash by signing the entrepreneurship support of HKUST.

  After deducting the rent of the factory building of 1,314,222 yuan, the company still has more than 10 million yuan on its books.

   Facing his teacher's questioning, Xu Yun scratched his head, and said calmly:

   "I don't want to save some money. Our company will have a lot of expenses in the future, and the money is all reserves."

   "Not to mention anything else, logistics, product cost, and production equipment are not small numbers."

   "When the company is on the right track, we will definitely set up laboratories and even R&D centers to gradually establish our own R&D system."

   "But now I haven't sold a single cockroach medicine, I'm as poor as an Internet writer, you see."

   "Go, go, young poor you."

  Tian Liangwei waved at him, then pondered for a moment, and said:

"Well, a few Micro-Matrix 36-well micro-bioreactors have just been installed in the yard not long ago, and the box has not been disassembled, and there is also a 350RPM orbital shaker. I will find someone to take you to the laboratory in a while. "

   "Hey, Micro-Matrix?"

  Xu Yun raised his eyelids, and looked at his teacher in surprise:

   "There is also a 350RPM orbital shaker? Teacher, when did you become so generous? Don't you have any conspiracy?"

   Facing Xu Yun's suspicious gaze, Tian Liangwei slightly dodged his eyes a few times, and took a sip of water tactically:

   "Don't think too much, there is no conspiracy, I just want you to try a new microfluidic interface nanoliter injection technology and high polymer feeding method by the way."

   "This is a new project that Professor Huang Qian's research group in the academy just completed a week ago. It happens to be short of Xiaobai. Ahem, the actual combat report in the laboratory, I thought of you."

   "To paraphrase Ren Danza, an old friend of mine who engages in blasting and a super blasting expert of the Academy of Engineering, it means, anyway, you don't need money, just try a little bit."

  Xu Yunjian said the corners of his mouth twitched a few times, and finally heaved a sigh:

   "Okay, just do as you said."

  It is not an easy task to conduct actual combat for others. Which link succeeds and which link fails, the failure situation, and data all need to be collected and summarized.

  Like the two technologies mentioned by Tian Liangwei, if they are practiced alone, together with equipment loss, each 150,000-200,000 is basically not enough.

   Seeing that Xu Yun agreed to his request, Tian Liangwei nodded in satisfaction.

   Then he thought of something, and took out a fax from the drawer:

   "By the way, President Hou's patent referral has been answered yesterday, and the patent has been officially approved, and the patent number is 20221"

   "However, considering the problem that the paper has not been published, the patent number has not been announced yet."

   "I inquired about the paper for you. It will be published in about one to two weeks. After all, it is a form of drafting, so just wait patiently for a few days."

   "By the way, Dean Hou asked me to tell you that the young man is very promising, work hard, and you can find him if you encounter any problems."

   "Dean Hou"

  Xu Yun took the fax and read the time, silently remembering Hou Xingyuan's favor in his heart.

  I may not have enough ability to help Hou Xingyuan at present, after all, he is a single-digit boss standing at the top of the scientific research pyramid of the Republic.

   Their figures went straight into the clouds, and Xu Yun could only look up for the time being.

  But with the completion of the halo mission, he believes that one day, he will be able to return this favor to Hou Xingyuan.

   Even one step closer, give the country a helping hand.

   This is not imaginary.

   Mentioned earlier.

  Before the dungeon mission appeared, Xu Yun's education was about to graduate with a Ph.D., and his ability was probably at the sub-high level.

  At that time, his goal was to recreate the footsteps of Academician Cao Xuetao, the president of Nankai University. At the age of 28, he was selected as a senior professional title, that is, a full professor.

  But with the use of the Mavericks Experience Card, Xu Yun's biological cognition has broken through to a new level.

  Ability is infinitely close to the high-level of popular majors, what is missing is only a job title selection process.

  If there are more rewards similar to thinking cards in the future, Xu Yun firmly believes that it will not be too long before he reaches the top of the pyramid.

   Then he chatted with Tian Liangwei about some other topics, and learned about the recent trends and arrangements in the school.

after an hour.

  Tian Liangwei received a fax from the school board:

   Agreed to conduct a scan of groundwater pipes on campus in an attempt to find entirely new microbial plants.

   Among them, the area of ​​the basketball court was handed over to Xu Yun, who was also assisted by the direct line of the University of Science and Technology—the school security team that accompanied him into Building 14 to collect cockroach corpses.

ten minutes later.

  Xu Yun, Qiu Sheng and Tian Liangwei bid farewell and left the office.

   And just as the two of them walked out of the medical building, Qiu Sheng suddenly let out a sigh, pointed in a certain direction and said:

   "Old Xu, look over there."

  Xu Yun followed the trend and looked.

  I saw this moment.

   A group of people were gathered under a tree not far away, as if they were watching something, and some people were taking pictures with their mobile phones.

   Eating melons is the instinct of everyone, even doctors are no exception. Xu Yun immediately patted Qiu Sheng on the shoulder:

   "Go, let's go and see!"

   Within two minutes, the two reached the edge of the crowd.

  As a result, as soon as they approached the crowd, a bunch of chirping discussions came from their ears:

   "It's strange, why do wild animals come in these days?"

   "It's not wild, our school is in the city center."

   "What happened to the city center, did you forget the wild boar from the year before last?"

   "The wild boar thing is not a good concept, it was sneaked in from the mountain when the whole country was closed."

   "It's only estimated that he escaped from some restaurant."

wild animals?

  Xu Yun heard this, a trace of curiosity flashed in his eyes.

   Is it a snake or a sheep?

   After all, if I remember correctly, there is a snake meat side furnace near the West District.

   At this moment, a boy in front of Xu Yun gave up his seat, so he took advantage of the opportunity to get into the front row.

  I saw this moment.

   Several security personnel were standing in the center of the crowd, pressing down with concerted efforts

   A donkey.

  Looking at this black donkey, for some reason, Xu Yun suddenly had a strange idea:

  Why does this donkey seem familiar?

   Just when he was wondering.

  The donkey that was crushed on the ground suddenly caught a glimpse of Xu Yun's face, and suddenly became excited, and its four hooves flapped rapidly:

   "Ou-oh-"

Note:

  Anyone can guess this easter egg, awesome!

  In other words, if there is a codeword live broadcast, will anyone watch it? You can chat without showing your face

   I cried, someone told me to reward the lord today, excitedly prepared to add more, and then found out that it was April Fool's Day.

   I'm still too naive QAQ.

  (end of this chapter)

Chapter end