Napoleon II Reborn Chapter 72

Alexander & #8226; Fleming (1881-1955), a professor at the Affiliated Medical School of Santmely Hospital in London, has long been researching repeatedly to invent a drug that can kill pathogenic bacteria. In 1928, as a research material, he cultivated the staphylococcus extracted from the patient's pus. He put the jelly mixed with the bacteria bait into a glass plate to cultivate the staphylococcus. Bacteria multiplied in large numbers, and communities of many bacteria gathered densely appeared on the jelly.

However, Fleming discovered an unexpected phenomenon. On the plate, there was a place covered with green mold, which began to spread around. Mold spores are always floating in the air, so when cultivating bacteria, special care should be taken not to allow mold to enter the plate. Even so, if you don't pay attention, mold will get in, take away the nutrients prepared for bacteria, and multiply quickly. Such things happen often. Once such a thing occurs, the cultivation will fail and we must start from scratch.

Fleming felt uncomfortable and wanted to pour out the contents of the dish. However, he happened to notice that there was no bacterial colony around Penicillium, and the empty space formed a circle. Fleming thought, this may be because the mold produced a special substance, and this substance spread to the surroundings, preventing the growth and reproduction of bacteria. He took the mold mixed in as a precious material and began to study it. Mold is called Penicillium fungus, is a precious species. He re-cultivated pure mold and proved that this mold hinders the growth and reproduction of various bacteria.

There is also survival competition among microorganisms, especially in the soil, there are countless microorganisms, and they are constantly fighting to the death. In the long-term evolution process, this mold has the ability to produce substances that kill other bacteria.

Fleming thought, could this substance be extracted from mold and used to kill pathogenic bacteria that enter the human body? So he grew the mold in broth, poured the broth containing the mold on the cultured colonies of bacteria, and the colonies died. Thus, he learned that the effective substance produced by mold can be dissolved in broth. He named this active substance penicillin.

Purification of penicillin was also needed, but Fleming was unsuccessful. After ten years, Oxford University professor Howard & #8226; Flory and his assistant Ernst & #8226; Ting finally succeeded in isolating penicillin from the broth. Penicillin saved the lives of countless patients. At the same time, it is also the starting point for the production and utilization of many antibiotics. The invention of penicillin was entirely the result of the accidental incorporation of mold spores, and it was also the result of Fleming's keen eyesight not ignoring this phenomenon.

In 1938, British pathologist Florey and biochemist Ernest. Jointly conducted research on the antibacterial effect of penicillin and drug purification, extracted high-purity penicillin and named it penicillin, and treated countless wounded infected and purulent wounds during the Second World War, saving the lives of thousands of soldiers. life. In 1945, Fleming, Florey and Ernest & #8226; King jointly won the Nobel Prize in Physiology of Medicine.

On the battlefields of the 19th century, various diseases and plagues threatened the lives of soldiers at all times, sometimes even surpassing the threat of the enemy. The level of medical care in this period was extremely low, and the number of doctors was much smaller than it is now. This situation is particularly prominent in the army. Many soldiers died due to lack of timely rescue after being injured, but the leaders of various countries did not pay attention to this at all, maybe they could not change this situation. Sometimes, human life is really worthless in this era.

Soldiers often died after surgery for serious injuries because there was no drug that could prevent wound infection. This situation was not resolved until the creation of penicillin. And because it saved the lives of tens of thousands of soldiers during World War II, it is known as the miracle medicine.

A long time ago, Xiao Jie was thinking about penicillin, but he was really not that kind of material. Although he knew how penicillin was discovered, he lacked the relevant knowledge and could not do it. In the war against the Third Anti-French Coalition, he witnessed the horror of war with his own eyes, and also knew how fragile the lives of ordinary soldiers are in war. As far as he knew, at least thousands of French soldiers died. They died because of wound infection after injury, let alone those from other countries. At that time, he was thinking that if penicillin was available, he could save the lives of thousands of soldiers.

After returning to Paris, he has been sorting out some of the information he knows. Although it is not complete, it is always better than nothing. So he found an opportunity to meet Kleist, a well-known French pharmacology expert at that time, with Kofit (it is purely fictional, Xiaoyu couldn't find relevant information, so he had to make up one randomly, everyone forgive me). The two talked secretly all afternoon in Kleist's small study. Outsiders didn't know what they were talking about at all. Even Cofete could only vaguely guess that Xiao Jie asked Kleist to help him develop a medicine. As for what kind of medicine? He didn't know what to use it for.

During the secret meeting between Xiao Jie and Kleist, Xiao Jie introduced the function and discovery process of penicillin in detail, UU Reading www. uukanshu.com and its impact on society. He also said that if Kleist is willing to conduct research in this area, he will provide him with a large amount of research funds, and the final patent right can also be given to him, but Xiao Jie has the priority to use this patent. In addition, this research must be kept secret, even if it is successful, unless similar drugs appear in other countries or the clinical trials are successful, and the research can only be made public after being discovered by other countries during use.

Kleist didn't know why Xiao Jie knew so much about this miraculous drug and put forward so many favorable conditions. He also knew from the prospect Xiao Jie described that once the drug was successfully developed, it would What kind of impact would it bring to the world, so in the face of this huge temptation, he quickly succumbed, accepted the conditions proposed by Xiao Jie, and started his research and development work.

When Xiao Jie and the others were preparing to establish the Andresi Group, Kleist's research still had no effect, but Xiao Jie was not in a hurry. He knew that any invention that would have a major impact on the world would not happen in a short while. At least he is already doing research in this area, which means that he is already ahead of the world once again. He firmly believed that sooner or later there would be a pharmaceutical factory under the Andresi Group that would bring him huge profits.

As long as penicillin can be developed, it will not only bring him amazing profits, but also be used as a strategic reserve. With penicillin, at least the survival rate of soldiers on the battlefield can be greatly improved, which plays an irreplaceable role in retaining these veterans who have been on the battlefield.

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